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    New biotech company giving private-sector boost to SA drug development research

    SolubleBioScience has yet to move its headquarters to San Antonio, but it's already having a direct impact on advancing drug development in the Alamo City. The Birmingham, Alabama-based biotech company, recently acquired by CytoBioscience, is contributing new technology to the Center for Innovative Drug Discovery that could prove to be a game changer for researchers and patients. SolubleBioScience, a new wholly owned subsidiary of CytoBioscience, has developed an instrument called ...
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    2 Predictors of Formulation Success Examined

    Protein-Protein Interaction Measurement: Balancing Complete Characterization with High-Throughput Capability in Formulation Development: Introduction High throughput screening in the world of pharmaceutical development has dramatically increased the number of approved drugs in the last 20 years, and drug developers increasingly use high throughput screening methods as a basis for lead evaluation. This is true in the area of formulation development for biologics, as well, and there are two metrics, Kd and ...
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    Southern Biologics Network Established to Create Biologics Faster and Less Expensively

    by Danielle Ragas, ProteoVac PR Birmingham, Baton Rouge, Raleigh and Research Triangle Park — Five biopharmaceutical research organizations with operations in Birmingham, Baton Rouge, Raleigh and Research Triangle Park have formed a new public-private partnership called the Southern Biologics Network (SBN) to create biologics faster and less expensively. The five research organizations will work together to create advanced biologics for biopharmaceutical companies of all sizes. Biologics are genetically engineered proteins ...
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    Protein solubility can be enhanced at various points along the production pipeline

    by Michelle Amaral, Science Writer This article, written by our Science Writer/PR Consultant, was published in the September 2013 issue of ON drugDelivery Magazine. We are excited that this issue will be circulated at the 3rd Annual PODD - Partnership Opportunities in Drug Delivery - Conference in Boston and at the CPhI Worldwide Pharma Expo CPhI Worldwide Pharma Expo In this piece, we summarize some of the techniques available for ...
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    Tackling the Problems of Insolubility

    by Carol Potera Companies developing Biosciences face the challenge of how to keep therapeutic proteins soluble, stable, and active. About half of all recombinant proteins are insoluble, a major hurdle for advancing them through drug discovery pipelines and into clinical trials. Unlike small molecule drugs, proteins also easily degrade. Whereas insolubility reduces the dose and effectiveness of biotherapeutics, degradation byproducts can cause serious side effects. Soluble Therapeutics Inc. uses its ...
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    Soluble Therapeutics, Inc. Awarded ~$1MM NIH Grant for Continued Development of the HSC™ Technology for Protein Formulation

    by BioSpace.com Birmingham, AL – 1 June 2012 - Soluble Therapeutics, Inc. a Birmingham, Alabama–based CRO specializing in formulation optimization for protein-based Bioscience announces a Phase II award of approximately $1MM from the NIH Small Business Technology Transfer Program (STTR). After closing a $1MM round of venture funding in the summer of 2011, this new infusion of capital will allow Soluble Therapeutics to accelerate the development and commercialization of the ...
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    Soluble Therapeutics Inc. Awarded $1M Grant

    by Staff Writer Innovation Depot News Birmingham-based Soluble Therapeutics Inc. has won a $1 million grant from the National Institutes of Health which will be used in the creation of a machine to help pharmaceutical companies in the drug development process. According to the Birmingham News, the biotechnology company, which is based at Innovation Depot, won the NIH grant as part of the Small Business Technology Transfer Program. The money ...
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    Soluble Therapeutics VC Streak Continues With $1M Infusion

    by Evan Belanger Soluble Therapeutics, a Birmingham-based biotech startup, has received $1 million in venture capital as it prepares to ramp up marketing its locally developed technology that dramatically speeds up the development of protein-based drugs and vaccines. University of Alabama at Birmingham , has also announced a new partnership with DiscoveryBioMed and Vivo Biosciences, both of Birmingham, to expand services offered to drug developers. Joseph Garner. Soluble was in ...
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