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    The Initial screen has been designed to:

    Determine the effect that individual additives have on the protein being formulated (ANN)

    between 30-50 additive are tested during the Initial Screen

    Identify the 9 additives that will promote the greatest solubility and physical stability

    Initial screen

    The Initial Screen begins the process of quantifying the effect that various solution additives have on the interaction of the client’s protein. SolubleBioScience utilizes a standard list of the most common additives used by crystallographers, vaccine manufacturers, and pharmaceutical developers. However, this list can be modified upon request*. The goal of the Initial Screen is to determine which of the additives have the effect on the protein that is desired by the investigator.

    Upon completion of the analysis, the investigator will receive an ordered list of the top five solutions most likely to accommodate his/her needs.